蒋西然，中国医科大学智能医学学院教授，曾获辽宁省第十二届青年科技奖、辽宁省第十二批“百千万人才工程”万人层次、沈阳市第四批高层次人才“拔尖人才”。2014年7月毕业于复旦大学，取得博士学位，2016年在美国Texas A&M大学电气和计算机工程系从事博士后工作，主要研究方向为医学人工智能、大数据分析和微流控芯片。发表第一作者或通讯作者SCI论文38篇、中文核心期刊论文10篇，获发明专利授权4项。主持完成了国家自然科学基金青年基金（81501833）、辽宁省科技厅博士启动基金（20170520252）和国家卫计委监督中心委托研究项目等多项课题研究工作。任中国医学影像整合联盟理事、辽宁省细胞生物学会功能影像专业委员会理事、中国研究型医院学会肿瘤影像专业委员会青年委员、中国医学影像整合联盟乳腺与女性生殖专委会委员、中国抗癌协会肿瘤影像专业委员会青年委员、辽宁省预防医学会环境卫生专业委员会委员、中国医师协会放射医师分会影像人工智能专委会委员等。主要从事基于人工智能的医学影像分析及智能医学辅助检测设备，通过与临床医院进行密切合作，充分发挥计算机工程学和临床医学相结合的优势，广泛开展智能化、精准化和微型化的医学检验分析新技术研究。

[1] 辽宁省自然科学基金面上项目（2021-MS-205），2021.07-2023.07

[2] 国家自然科学基金青年基金（81501833），2016.01-2018.12

[3] 沈阳市教科工委2020年高校“双服务”重点项目，2020.06-2020.11

[4] 健康医疗大数据研究课题（HMB201903101），2019.02-2021.12

[5] 辽宁省科技厅博士启动基金（20170520252），2017.09-2019.08

[6] 国家重点研发计划专项子课题，2021.5.18-2023.9.9

(1) Ying Fan#, Xinti Wang#, Chunna Yang#, Huanhuan Chen, Huan Wang, XiaoyuWang, Shaoping Hou, Lihua Wang, YahongLuo, Xianzheng Sha, Huazhe Yang*, TaoYu*, Xiran Jiang*. Brain-tumorinterface-based MRI radiomics models to determine EGFR mutation, response toEGFR-TKI and T790M resistance mutation in non-small cell lung carcinoma brainmetastasis. Journalof Magnetic Resonance Imaging. 2023.04. Online. IF 5.119 二区

(2) Ying Fan #, Xinti Wang #, Yue Dong #, Enuo Cui, Huan Wang, Xinyan Sun,Juan Su, Yahong Luo, Tao Yu*, XiranJiang*. Multiregional radiomics of brain metastasis can predict response toEGFR-TKI in metastatic NSCLC. European Radiology. 2023.03. Online. IF 7.034 二区 DOI: 10.1007/s00330-023-09709-7

(3) Chongwei Wu#, Langyuan Fu#, Zhiying Tian, Jiao Liu, Jiangdian Song, WeiGuo, Yu Zhao, Duo Zheng, Ying Jin, Dongxu Yi, Xiran Jiang*. LWMA-Net:Light-weighted Morphology Attention Learning for Human Embryo Grading. Computersin Biology and Medicine. 2022. 151. IF 6.698 一区 DOI: 10.1016/j.compbiomed.2022.106242

(4) Ying Fan, Zilong Zhao, Xingling Wang, Hua Ai, Chunna Yang, Yahong Luo*,Xiran Jiang*. Radiomicsfor prediction of response to EGFR-TKI based on metastasis/brain parenchyma(M/BP)-interface. Radiologia Medica. 2022,127(12):1342-1354. IF 6.313 二区 DOI: 10.1007/s11547-022-01569-3

(5) Ying Fan, Lingzi He, Huazhe Yang, Yan Wang, Juan Su, Shaoping Hou,Yahong Luo, Xiran Jiang*.Preoperative MRI-based radiomics of brain metastasis to assess T790M resistancemutation after EGFR-TKI treatment in NSCLC. Journal of Magnetic ResonanceImaging.2022, 09. Online. IF 5.119 二区DOI:10.1002/jmri.28441

(6) Tao Jiang, Xinyan Sun, Yue Dong, Wei Guo, Hongbo Wang, Zhibin Yue,Yahong Luo, Xiran Jiang*. Deeplearning for preoperative prediction of the EGFR mutation and subtypes based onthe MRI image of spinal metastases from primary NSCLC. Biomedical Signal Processing andControl. 2022. 08 Online. IF 5.076 二区 DOI: 10.1016/j.bspc.2022.104084

(7) Ying Fan, Yue Dong, Xinyan Sun, Huan Wang, Peng Zhao, Hongbo Wang, Xiran Jiang *. Development andvalidation of MRI-based radiomics signatures as new markers for preoperativeassessment of EGFR mutation and subtypes from bone metastases. BMC Cancer.2022. 22(1): 889. IF=4.638 二区 DOI: 10.1186/s12885-022-09985-4

(8) Jiaxin Shi, Zilong Zhao, Tao Jiang, Hua Ai, Jiani Liu, Xinpu Chen,Yahong Luo, Huijie Fan*, Xiran Jiang*. A deep learning approach withsubregion partition in MRI image analysis for metastatic brain tumor. Frontiers in Neuroinformatics.2022. 16: 973698. IF=3.739 二区 DOI: 10.3389/fninf.2022.973698

(9) Ying Fan#, Yue Dong#, Huan Wang, Hongbo Wang, Xinyan Sun, Xiaoyu Wang,Peng Zhao, Yahong Luo, Xiran Jiang*.Development and externally validate MRI-based nomogram to assess EGFR and T790Mmutations in patients with metastatic lung adenocarcinoma. European Radiology. 2022,32(10):6739-6751.IF 7.034 二区 DOI: 10.1007/s00330-022-08955-5

(10) Ran Cao, Ziyan Pang, Xiaoyu Wang, Zhe Du, Huanhuan Chen, Jiani Liu,Zhibin Yue, Huan Wang, Yahong Luo, XiranJiang*. Radiomics evaluates the EGFR mutation status from the brainmetastasis: a multi-center study. Physics in Medicine and Biology.2022, 67(12). IF 4.174 二区 DOI: 10.1088/1361-6560/ac7192

(11) Zhibin Yue, Xiaoyu Wang, Tao Yu, Shengjie Shang, Guanyu Liu, WenwenJing, Huazhe Yang, Yahong Luo*, XiranJiang*. Multi-parametric MRI-based radiomics for the diagnosis of malignantsoft-tissue tumor.  Magnetic Resonance Imaging.2022, 91: 91-99. IF 3.131 四区 DOI: 10.1016/j.mri.2022.05.003

(12) Tao Jiang, Shuai He, Huazhe Yang, Yue Dong, Tao Yu, Yahong Luo*, Xiran Jiang*. Multiparametric MRI-basedradiomics for the prediction of microvascular invasion in hepatocellularcarcinoma. Acta Radiologica. 2022.3. Online. IF 1.701 四区 DOI: 10.1177/02841851221080830

(13) Jiaxin Shi, Yue Dong, Wenyan Jiang, Fengying Qin, Xiaoyu Wang, LinpengCui, Yan Liu, Ying Jin, Yahong Luo, XiranJiang*. MRI-based peritumoral radiomics analysis for preoperativeprediction of lymph node metastasis in early-stage cervical cancer: amulti-center study. Magnetic Resonance Imaging. 2022. 88: 1-8. IF 3.131 四区 DOI: 10.1016/j.mri.2021.12.008

(14) Tao Jiang, Jiangdian Song, Xiaoyu Wang, Shuxian Niu, Nannan Zhao, YueDong, Xingling Wang, Yahong Luo, XiranJiang*. Intratumoral and peritumoral analysis of mammography,tomosynthesis, and multiparametric MRI for predicting Ki-67 level in breastcancer: a radiomics-based study. Molecular Imaging and Biology. 2022, 4: 550-559. IF3.484 三区 DOI: 10.1007/s11307-021-01695-w

(15) Tao Jiang, Wenyan Jiang, Shijie Chang, Hongbo Wang, Shuxian Niu,Zhibin Yue, Huazhe Yang, Xiaoyu Wang, Nannan Zhao, Siqi Fang, Yahong Luo, Xiran Jiang*. Intratumoralanalysis of digital breast tomosynthesis for predicting the Ki-67 level inbreast cancer: a multi-center radiomics study. Medical Physics. 2022,49(1): 219-230 IF 4.072 三区 DOI: 10.1002/mp.15392

(16) Jiaxin Shi, Linpeng Cui, Hongbo Wang, Yue Dong, Tao Yu, Huazhe Yang,Xingling Wang, Guanyu Liu, Wenyan Jiang, Yahong Luo, Zhiguang Yang*, Xiran Jiang*. MRI-based intratumoraland peritumoral radiomics on prediction of lymph-vascular space invasion incervical cancer: A multi-center study. Biomedical Signal Processing and Control.2022. 72: 103373 IF 5.076 二区DOI: 10.1016/j.bspc.2021.103373

(17) Ying Fan, Yue Dong, Huazhe Yang, Huanhuan Chen, Yalian Yu, XiaoyuWang, Xingling Wang, Tao Yu, Yahong Luo, XiranJiang*. Subregional radiomics analysis for the detection of the EGFRmutation on thoracic spinal metastases from lung cancer. Physics in Medicine and Biology.2021, 66(21): 215008. IF 4.174 二区 DOI: 10.1088/1361-6560/ac2ea7

(18) Yuan Cheng#, Yahong Luo#, Yue Hu#, Zhaohe Zhang, Xingling Wang, QingYu, Guanyu Liu, Enuo Cui, Tao Yu, Xiran Jiang*.Multiparametric MRI-based Radiomics approaches on predicting response toneoadjuvant chemoradiotherapy (nCRT) in patients with rectal cancer. AbdominalRadiology. 2021, 46(11): 5072–5085. IF 3.039 三区 DOI: 10.1007/s00261-021-03219-0

(19) Meihong Ren, Huazhe Yang, Qingyuan Lai, Dabao Shi, Guanyu Liu, XueShuang, Juan Su, Liping Xie, Yue Dong*, XiranJiang*. MRI-based radiomics analysis for predicting the EGFR mutation basedon thoracic spinal metastases in lung adenocarcinoma patients. MedicalPhysics. 2021, 48(9):5142-5151. IF 4.072 三区 DOI: 10.1002/mp.15137

(20) Chongwei Wu, Wei Yan, Hongtu Li, Jiaxin Li, Hongkai Wang, ShijieChang, Tao Yu, Ying Jin, Chao Ma, Yahong Luo, Dongxu Yi*, Xiran Jiang*. A classification system of day 3 human embryos usingdeep learning. BiomedicalSignal Processing and Control. 2021, 70: 102943. IF 5.076 二区 DOI:10.1016/j.bspc.2021.102943

(21) Ran Cao, Yue Dong, Xiaoyu Wang, Meihong Ren, Xingling Wang, NannanZhao, Tao Yu, Lu Zhang, Yahong Luo, E-Nuo Cui, Xiran Jiang*. MRI-based radiomics nomogram as a potential biomarkerto predict the EGFR mutations in exon 19 and 21 based on thoracic spinalmetastases in lung adenocarcinoma. Academic Radiology. 2022.29(3):e9-e17. IF 5.482 三区 DOI: 10.1016/j.acra.2021.06.004

(22) Shuxian Niu, Xiaoyu Wang, Nannan Zhao, Guanyu Liu, Yangyang Kan, YueDong, Enuo Cui, Yahong Luo, Tao Yu*,Xiran Jiang*. Radiomic evaluations of the diagnostic performance of DM,DBT, DCE MRI, DWI and their combination for the diagnosis of breast cancer. Frontiersin Oncology. 2021, 11: 725922. IF5.738 三区 DOI:10.3389/fonc.2021.725922

(23) Shuxian Niu, Wenyan Jiang, Nannan Zhao, TaoJiang, Yue Dong, Yahong Luo, Tao Yu*, XiranJiang*. Intra- and peritumoral radiomics on assessment of breast cancermolecular subtypes based on mammograph and MRI. Journal of Cancer Research andClinical Oncology. 2022, 148(1):97-106. IF 4.553 三区 DOI: 10.1007/s00432-021-03822-0

(24) ShuxianNiu, Tao Yu, Yan Cao, Yue Dong, Yahong Luo*, Xiran Jiang*. Digitalbreast tomosynthesis-based peritumoral radiomics approaches in thedifferentiation of benign and malignant breast lesions. Diagnostic and Interventional Radiology. 2022, 28(3): 217-225. IF3.346 四区 DOI: 10.5152/dir.2022.20664

(25) Linpeng Cui, Tao Yu, Yangyang Kan, Yue Dong, Yahong Luo*, Xiran Jiang*. Multi-parametricMRI-based peritumoral radiomics on prediction of lymph-vascular space invasionin early-stage cervical cancer. Diagnostic and Interventional Radiology.2022, 28(4):312-321 IF 3.346 四区 DOI: 10.5152/dir.2022.20657

(26) ShengjieShang, Jing Sun, Zhibin Yue, Yingni Wang, Xiaoyu Wang, Yahong Luo, Dazhe Zhao,Tao Yu*, Xiran Jiang*. Multi-parametric MRI based radiomics with tumorsubregion partitioning for differentiating of benign and malignant soft-tissuetumors. Biomedical Signal Processing and Control. 2021, 67:102522. IF 5.076二区 DOI:10.1016/j.bspc.2021.102522

(27) Xiran Jiang, Meihong Ren, XueShuang, Huazhe Yang, Dabao Shi, Qingyuan Lai, Yue Dong*. Multi-parametricMRI-based radiomics approaches for preoperative prediction of EGFR mutation statusin spinal bone metastases in patients with lung adenocarcinoma. Journalof Magnetic Resonance Imaging. 2021, 54(2): 497-507. IF 5.119二区  DOI: 10.1002/jmri.27579

(28) Enuo Cui, Tao Yu, Shengjie Shang, Xiaoyu Wang, Yilin Jin, Yue Dong,Hai zhao, Yahong Luo, Xiran Jiang*.Radiomics model for distinguishing tuberculosis and lung cancer on computedtomography scans. World Journal of Clinical Cases. 2020, 8(21): 5203-5212. IF 1.337四区 DOI: 10.12998/wjcc.v8.i21.5203

(29) Zhaohe Zhang# , Xiran Jiang#(并列一作), Rui Zhang, Tao Yu, Shanshan Liu, Yahong Luo*. Radiomics signature as anew biomarker in preoperative prediction of a response to neoadjuvantchemoradiotherapy in locally advanced rectal cancer. Diagnostic and InterventionalRadiology. 2021.27: 308-314. IF 2.630四区 DOI:10.5152/dir.2021.19677

(30) Xiran Jiang, Jiaxin Li,Yangyang Kan, Tao Yu, Shijie Chang, Xianzheng Sha, Hairong Zheng, Yahong Luo*, ShanshanWang*. MRI based radiomics approach with deep learning for prediction of vesselinvasion in early-stage cervical cancer. IEEE-ACMTransactions on Computational Biology and Bioinformatics. 2021, 3(18):995-1002. IF 3.710 三区DOI:10.1109/TCBB.2019.2963867

(31) Xiaoxi Wang, Shengjie Shang, Huazhe Yang, Hua Ai, Yin Wang, ShijieChang, Xianzheng Sha, Lie Wang, XiranJiang*. Associations of psychological distress withpositive psychological variables and activities of daily living among strokepatients: a cross-sectional study. BMC Psychiatry. 2019,19(1): 381. IF 2.704 三区 DOI: 10.1186/s12888-019-2368-0

(32) Xiran Jiang, Xiaoya Zhou, Qi Liu, Lulu Zheng, Ning Yu, Wenli Li*. Expressions of Acidothermus cellulolyticus ThermostableCellulases in Tobacco and Rice Plants. Biotechnology & BiotechnologicalEquipment. 2017, 1(31): 23-28. IF:1.762 四区DOI:10.1080/13102818.2016.1236671

(33) Xiran Jiang, Yingchao Liu,Qi Liu, Wenwen Jing, Kairong Qin, Guodong Sui*. Rapid Capture and Analysis ofAirborne Staphylococcus aureus in theHospital using A Microfluidic Chip. Micromachines. 2016, 7(9), 169. IF: 2.426 三区 DOI: 10.3390/mi7090169

(34) XiranJiang, Wenwen Jing, Xiaoting Sun, Qi Liu, Chunguang Yang,Sixiu Liu, Kairong Qin, Guodong Sui*. High-throughputmicrofluidic device for LAMP analysis of airborne bacteria. ACSSensors. 2016, 1(7): 958-962. IF7.333一区 DOI:10.1021/acssensors.6b00282

(35) XiranJiang, Wenwen Jing, Lulu Zheng, Sixiu Liu, Wenjuan Wu, GuodongSui*. A Continuous-flow high-throughput microfluidic device for airbornebacteria PCR detection. Lab on a Chip. 2014, 14: 671-676. IF 6.774一区 DOI: 10.1039/c3lc50977j

(36) Wenwen Jing#, Xiran Jiang#(并列一作), Wang Zhao, Sixiu Liu, Xunjia Cheng, Guodong Sui*. Microfluidic platformfor direct capture and analysis of airborneMycobacterium tuberculosis. Analytical Chemistry. 2014, 86(12):5815-5821. IF 5.886一区 DOI: 10.1021/ac500578h

(37) XiranJiang, Ning Shao, Wenwen Jing, Shengce Tao, Sixiu Liu, GuodongSui*. Microfluidic chip integrating high throughput continuous-flow PCR and DNAhybridization for bacteria analysis. Talanta. 2014, 122: 246-250.  IF 4.916 二区 DOI: 10.1016/j.talanta.2014.01.053

辽宁省第十二批“百千万人才工程”万人层次、沈阳市第四批高层次人才“拔尖人才”