1.  主持国家自然科学基金项目、81971400、鞭毛内运输蛋白IFT88调节初级纤毛结构进而调控Wnt信号通路在宫内发育迟缓子代肾脏发育不良中的作用机制研究2020/01-2023/12、56万元。

2.  主持国家自然科学基金项目、81571449、SIRT1调控未折叠蛋白反应及自噬在宫内生长受限子代代谢综合征发生中的作用机制研究2016/01-2019/12、53万元。

3.  主持国家自然科学基金项目, 81370716、FoxA2 调控KATP通道在宫内生长受限子鼠代谢综合征发生中的作用机制研究、2014/01-2017/12、70万元。

4.  主持国家自然科学基金项目, 81100432、下丘脑PI3K-KATP信号通路异常对宫内生长受限子代外周糖代谢影响的研究、2012/01-2014/12、23万元。

5.   主持中国医科大学附属盛京医院自由研究者项目，2018/01-2022/12，100万元。

6.  主持辽宁省科技厅支持中国医科大学高质量发展基金项目，2023/06-2025/06，5万元。

7.   主持辽宁省自然基金指导计划项目，初级纤毛与自噬相互调控影响下游Wnt信号通路在宫内生长受限子代肾脏发育中的作用机制研究2019-ZD-0754 2019/01-2021/12，5万元。

近5年以第一作者或通讯作者发表论文

1.      Yanyan Guo, Pei Zhou, Lei Qiao, Hongbo Guan, Jian Gou,Xiaomei Liu, Maternal protein deficiency impairs peroxisome biogenesis andleads to oxidative stress and ferroptosis in liver of fetal growth restrictionoffspring, The Journal of Nutritional Biochemistry, 2023, 121, 109432. 

2.      JunWang, Pei Zhou, Liangliang Zhu, Hongbo Guan, Jian Gou, Xiaomei Liu. Maternalprotein deficiency alters primary cilia length in renal tubular and impairskidney development in fetal rat. Front. Nutr.,2023,10. 

3.      HongboGuan, Pei Zhou, Ying Qi, Huan Huang, Jun Wang, Xiaomei Liu. Cigarettesmoke-induced trophoblast cell ferroptosis in rat placenta and the effects ofL-arginine intervention, Ecotoxicology and Environmental Safety, 2022, 243,114015. 

4.      PeiZhou, Hongbo Guan, Yanyan Guo, Liangliang Zhu, Xiaomei Liu.Maternal High-FatDiet Programs Renal Peroxisomes and Activates NLRP3 Inflammasome-MediatedPyroptosis in the Rat Fetus，Article,Journal of Inflammation Research ，2021:145095–5110. 

5.      HongboGuan, Yanyan Guo , Liangliang Zhu , Yisheng Jiao, Xiaomei Liu1*. PeroxisomeDeficiency Dysregulates Fatty Acid Oxidization and Exacerbates Lipotoxicity inβ Cells. Oxidative Medicine and Cellular Longevity, 2021, 7726058. 

6.      YanyanGuo, Yan Lu, Jun Wang, Liangliang Zhu, Xiaomei Liu*. Dysregulated ion channelsand transporters activate endoplasmic reticulum stress in rat kidney of fetalgrowth restriction. Life Sciences, 2020, 118276.

7.      XiaomeiLiu*,Yanyan Guo,Jun Wang, Liangliang Zhu, Linlin Gao. Dysregulation in theUnfolded Protein Response in the FGR Rat Pancreas. International Journal ofEndocrinology, 2020,5759182 . 

8.      XiaomeiLiu*,Yanyan Guo,Jun Wang,Linlin Gao,Caixia Liu.Label-free proteomics of thefetal pancreas identifies deficits in the peroxisome in rats with intrauterinegrowth restriction. Oxidative Medicine and Cellular Longevity,2019. 

9.      XiaomeiLiu, Jun Wang, Linlin Gao, Yisheng Jiao, Caixia Liu. Maternal proteinrestriction induces alterations in hepatic unfolded protein response-relatedmolecules in adult rat offspring. Front. Endori,2018,6（1）:676. 

10.   JunWang, Hao Liu, Linlin Gao, Xiaomei Liu*. Impaired FGF10 signaling andepithelial development in experimental lung hypoplasia with esophageal atresia.Front. Pediatr.,2018,6（1）:109.