1.2022年辽宁省应用基础研究计划项目

项目名称：单纯疱疹病毒性角膜炎免疫发病机制与免疫治疗的研究

本人名次：第一负责人        资助强度：30万元

2.2018年度辽宁省自然科学基金计划重点项目

项目名称：TRIM家族分子TRIM21调控树突状细胞分化和炎性因子表达及其对HSV-1潜伏感染的作用机制研究  项目性质：纵向

本人名次：第一负责人        资助强度：5万元 

3. 2020年度辽宁省重点研发联合资助计划项目

 脱细胞角膜基质透镜移植治疗严重感染性角膜病变的临床研究

本人名次：第一负责人        资助强度：30万元

4.辽宁省自然科学基金计划重点项目

 TRIM家族分子TRIM21调控树突状细胞分化和炎性因子表达及其对HSV-1潜伏感染的作用机制研究

 本人名次：第一负责人        资助强度：5万元 

1. Wang X, Xia L. Effect of macular vascular density on visual quality in young myopic adults. Front Med (Lausanne). 2022;9:950731. Published 2022 Aug 16. doi:10.3389/fmed.2022.950731

2. Liu Z, Xia L. E3 ligase RNF5 inhibits type I interferon response in herpes simplex virus keratitis through the STING/IRF3 signaling pathway. Front Microbiol. 2022;13:944101. Published 2022 Aug 2. doi:10.3389/fmicb.2022.944101

3. Tan T, Xia L. TRIM21 Aggravates Herpes Simplex Virus Epithelial Keratitis by Attenuating STING-IRF3-Mediated Type I Interferon Signaling. Front Microbiol. 2020;11:703. Published 2020 Apr 16. doi:10.3389/fmicb.2020.00703

4. Wang X, Xia L. Evaluation of the Effects of Myopic Astigmatism Correction and Anterior Corneal Curvature on Functional Optical Zone After SMILE. J Refract Surg. 2023;39(2):135-141. doi:10.3928/1081597X-20221215-01

5. Xia L, Tan T, Li Y, Zhong Q, Shi M. Blockade of IL-27 signaling ameliorates herpes stromal keratitis with upregulated CD4+ Foxp3+ regulatory T cells influx in mice. Indian J Ophthalmol. 2019;67(11):1821-1828. doi:10.4103/ijo.IJO_1780_18

6. Xia L, Zhang S, Cao Z, Hu Y, Yang H, Wang D. Interleukin-17 enhanced immunoinflammatory lesions in a mouse model of recurrent herpetic keratitis. Microbes Infect. 2013;15(2):126-139. doi:10.1016/j.micinf.2012.10.017

7. Xia LK, Yu J, Chai GR, Wang D, Li Y. Comparison of the femtosecond laser and mechanical microkeratome for flap cutting in LASIK. Int J Ophthalmol. 2015;8(4):784-790. Published 2015 Aug 18. doi:10.3980/j.issn.2222-3959.2015.04.25

8. Xia LK, Ma J, Liu HN, Shi C, Huang Q. Three-year results of small incision lenticule extraction and wavefront-guided femtosecond laser-assisted laser in situ keratomileusis for correction of high myopia and myopic astigmatism. Int J Ophthalmol. 2018;11(3):470-477. Published 2018 Mar 18. doi:10.18240/ijo.2018.03.18

9. Ma J, Cao NJ, Xia LK. Efficacy, safety, predictability, aberrations and corneal biomechnical parameters after SMILE and FLEx: Meta-analysis. Int J Ophthalmol. 2016;9(5):757-762. Published 2016 May 18. doi:10.18240/ijo.2016.05.22

10. Xia L, Zhang S, Zhou J, Li Y. A crucial role for B and T lymphocyte attenuator in preventing the development of CD4+ T cell-mediated herpetic stromal keratitis. Mol Vis. 2010;16:2071-2083. Published 2010 Oct 13.