1. 辽宁省科学技术厅支持中国医科大学高质量发展科技资金项目：外泌体S100A10在肝细胞癌转移微环境中的作用研究，资助金额：100万元，主持（2023-2025）。

2. 辽宁省科学技术厅优秀青年基金计划：肝细胞癌干性相关外泌体重塑肿瘤微环境的机制研究，资助金额：50万元，主持（2024-2026）。

3. 国家自然科学基金委员会，青年项目：外泌体S100A10通过调控巨噬细胞分化重塑肝细胞癌免疫微环境的分子机制研究，资助金额：30万元，主持（2026-2028）。

(1) Xia Wang, Hongyang Huang, Karen Man-Fong Sze, Jin Wang, Lu Tian, Jingyi Lu, Yu-Man Tsui, Hoi Tang Ma, Eva Lee, Ao Chen, Joyce Lee, Ying Wang, Judy Wai Ping Yam, Tan-To Cheung, Xin-Yuan Guan, Irene Oi-Lin Ng*, S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos, Gut, 2023, 327998(gutjnl-20).

(2) Xia Wang, Jin Wang, Yu-Man Tsui, Chaoran Shi, Ying Wang, Xin Zhang, Qian Yan, Miao Chen, Chen Jiang, Yun-Fei Yuan, Chun-Ming Wong, Ming Liu, Zeng-yu Feng, Honglin Chen, Irene Oi Lin Ng, Lingxi Jiang*, Xin-Yuan Guan*, RALYL increases hepatocellular carcinoma stemness by sustaining the mRNA stability of TGF-β2, Nature Communications, 2021, 12(1): 1518.

(3) Lingxi Jiang#, Xia Wang#, Fangfang Ma#, Xuelong Wang#, Minmin Shi, Qian Yan, Ming Liu, Juan Chen, Chaoran Shi, Xin-Yuan Guan*, PITX2C increases the stemness features of hepatocellular carcinoma cells by up-regulating key developmental factors in liver progenitor, Journal of Experimental & Clinical Cancer Research, 2022, 41(1).

(4) Xia Wang#, Lu Tian#, Jingyi Lu, Irene Oi-Lin Ng*, Exosomes and cancer-Diagnostic and prognostic biomarkers and therapeutic vehicle, Oncogenesis, 2022, 11(1).

(5) Jin Wang#, Bohang Yin#, Jiabing Lian, and Xia Wang*, Extracellular Vesicles as Drug Delivery System for Cancer Therapy, Pharmaceutics, 2024, 16, 1029.

(6) Wang, Xia, Ding, Xiaoling, Nan, Lijuan, Wang, Yiting, Wang, Jing, Yan, Zhiqiang, Zhang, Wei, Sun, Jihong, Zhu, Wei, Ni, Bing, Dong, Suzhen*, Yu, Lei*, Investigation of the roles of exosomes in colorectal cancer liver metastasis, ONCOLOGY REPORTS, 2015, 5(33): 2445-2453.

(7) Ao Chen#, Vanilla Xin Zhang#, Qingyang Zhang, Karen Man-Fong Sze, Lu Tian, Hongyang Huang, Xia Wang, Eva Lee, Jingyi Lu, Xueying Lyu, Man-Fong Joyce Lee, Chun Ming Wong, Daniel Wai-Hung Ho, Irene Oi-Lin Ng*, Targeting the oncogenic m6A demethylase FTO suppresses tumourigenesis and potentiates immune response in hepatocellular carcinoma, Gut 2025;74:90–102.

(8) Hongyang Huang#, Yu-Man Tsui#, Daniel Wai-Hung Ho, Clive Yik-Sham Chung, Karen Man-Fong Sze,  Eva Lee, Gary Cheuk-Hang Cheung, Vanilla Xin Zhang, Xia Wang, Xueying Lyu, Irene Oi-Lin Ng*, LANCL1, a cell surface protein, promotes liver tumor initiation through FAM49B-Rac1 axis to suppress oxidative stress, Hepatology. 2024;79:323–340.

(9) Yung-Tuen Chiu#, Abdullah Husain#, Karen Man-Fong Sze, Daniel Wai-Hung Ho, Eliana Mary Senires Suarez, Xia Wang, Eva Lee, Hoi-Tang Ma, Joyce Man-Fong Lee, Lo-Kong Chan, Irene Oi-Lin Ng*, Midline 1 interacting protein 1 promotes cancer metastasis through FOS-like 1-mediated matrix metalloproteinase 9 signaling in HCC, Hepatology. 2023;78:1368–1383.

(10) Xiwei Wang, Zheng Xiang, Yinping Liu, Chunyu Huang, Yujun Pei, Xia Wang, Hui Zhi, Wilfred Hing-Sang Wong, Haiming Wei, Irene Oi-Lin Ng, Pamela Pui-Wah Lee, Godfrey Chi-Fung Chan, Yu-Lung Lau, Wenwei Tu*, Exosomes derived from Vδ2-T cells control Epstein-Barr virus-associated tumors and induce T cell antitumor immunity, Science Translational Medicine, 2020, 12(563).

(11) Ying Wang, Zhaojie Lyu, Yanru Qin, Xia Wang, Liangzhan Sun, Yu Zhang, Lanqi Gong, Shayi Wu, Shuo Han, Ying Tang, Yongxu Jia, Dora Lai-Wan Kwong, NgarWoon Kam, Xin-Yuan Guan*, FOXO1 promotes tumor progression by increased M2 macrophage infiltration in esophageal squamous cell carcinoma, Theranostics, 2020, 10(25): 11535-11548.

(12) Lu Tian, Luqing Zhao, Karen Man-Fong Sze, Charles Shing Kam, Vanessa Sheung-In Ming, Xia Wang, Vanilla Xin Zhang, Daniel Wai-Hung Ho, Tan-To Cheung, Lo-Kong Chan*, Irene Oi-Lin Ng*, Dysregulation of RalA signaling through dual regulatory mechanisms exerts its oncogenic functions in hepatocellular carcinoma., Hepatology, 2021, 2021(00): 1-18.

(13) Qian Yan#, Yu Zhang#, Xiaona Fang#, Beilei Liu, Tin Lok Wong, Lanqi Gong, Shan Liu, Dandan Yu, Ming Liu, Lingxi Jiang, Xia Wang, Ting Wei, Yongxu Jia, Lei Li, Liangzhan Sun, Ying Tang, Ningning Zhou, Yun-Fei Yuan, Yan Li, Stephanie Ma, Xin-Yuan Guan*, PGC7 promotes tumor oncogenic dedifferentiation through remodeling DNA methylation pattern for key developmental transcription factors, Cell Death & Differentiation, 2021, 28(6): 1955-1970.

(14) Chaoran Shi#, Dora L.W. Kwong#, Xue Li#, Xia Wang, Xiaona Fang, Liangzhan Sun, Ying Tang, Xin-Yuan Guan*, Shan-Shan Li*, MAEL Augments Cancer Stemness Properties and Resistance to Sorafenib in Hepatocellular Carcinoma through the PTGS2/AKT/STAT3 Axis, Cancers, 2022, 14(12): 2880- 2880.